Dr. Lei Liu

Institute for Advanced Materials Jiangsu University China

Mobile: +8618206102793

E-mail: liul@ujs.edu.cn

Education Background

Sep. 2005-Jun. 2010    PhD, Nano-Biomedicine National Center for Nanoscience and Technology, China

Sep. 2010-Aug. 2013 Post-doc iNANO center Aarhus University Denmark

Dec. 2013-now         Young Distinguish Professor, Institute for Advanced Materials, Jiangsu University

Dec.2014-now.         Jiangsu Specially-Appointed Professor. China

Research Experiences

1. Amyloid protein

2. Scanning probe microscopy and application in biology

3. Antimicrobial nanomaterials and biomaterials

4. Peptide based nanomaterials

   Academic activities:

5. Guest editor of Journal of nanomaterials

6. Peer review of ACS, RSC, Nature publishing group, ete

7. Chair of special session in 3M-NANO 2015 international conference

8. Chair of special session in SIS 2016 international conference

9. Standard committee of 3M-NANO 2017 international conference

Selected publication:

1. Jakob Knudsen, Lei Liu，et al, Routing of individual polymers in designed patterns. Nature Nanotech. 2015, 10, 892-899. (Front Cover paper)

2. Lei Liu*，Xiaohua Tian, Yue Ma, Yuqing Duan, Xin Zhao, Guoqing Pan*. A Versatile Mussel-Inspired Dynamic Biointerface: From Specific Cell Behavior Modulation to Selective Cell Isolation. Angew.Chem.-Int. Ed. 2018, 57, 7878-7882

3. Lei Liu, Lasse Hyldgaard Klausen, Dong MD*. Two-dimensional peptide based functional nanomaterials. Nano Today, 2018, 23, 40~58

4. Lei Liu^#, Qiang Li^#, Shuai Zhang^#, Xiaofeng Wang, Søren Vrønning Hoffmann, Jingyuan Li, Zheng Liu, Flemming Besenbacher*, Mingdong Dong*, Identification of a novel parallel β-stand conformation within molecular monolayer of amyloid peptide, Advanced Science, 2016, 1500369, 1-10. (Frontispiece)

5. Lin Niu^#, Lei Liu^# (equal contribution), Wenhui Xi^#, Qiusen Han, Qiang Li, Yue Yu, Qunxing Huang, Fuyang Qu, Meng Xu, Yibao Li, Huiwen Du, Rong Yang, Jacob Cramer, Kurt V. Gothelf, Mingdong Dong, Flemming Besenbacher, Qingdao Zeng, Chen Wang*, Guanghong Wei*, Yanlian Yang*. Synergistic inhibitory effect of Peptide-Organic Co-assemblies on Amyloid Aggregation. ACS Nano, 2016, 10, 4143−4153.

6. Lei Liu^#, Lin Niu^#, Meng Xu, Qiusen Han, Hongyang Duan, Mingdong Dong, Flemming Besenbacher, Chen Wang,* and Yanlian Yang*. Molecular tethering effect of C-terminus of amyloid peptide Aβ42. ACS Nano. 2014, 8, 9503-9510.

7. Lei Liu, Lang Zhang, Lin Niu，Meng Xu, XiaoBo Mao, Yanlian Yang* and Chen Wang*. Observation of Reduced Cytotoxicity of Aggregated Amyloidogenic Peptides with Chaperone-like Molecules. ACS Nano. 2011, 5, 6001-6007.

8. Lei Liu, Lan Zhang, Xiaobo Mao, Lin Niu, Yanlian Yang*, Chen Wang*. Chaperon-mediated single molecular approach towards modulating Aβ peptide aggregation. Nano Lett. 2009, 9, 4066-4072.

9. P Zhang, Z Wang, L Liu*, LH Klausen, Y Wang, J Mi, M Dong*. Modulation the electronic property of 2D monolayer MoS2 by amino acid. Applied Materials Today. 2019, 14, 151-158.

10. Y Feng, Q Chen, Q Yin, G Pan, Z Tu, L Liu*. Reduced Graphene Oxide Functionalized with Gold Nanostar Nanocomposites for Synergistically Killing Bacteria through Intrinsic Antimicrobial Activity and Photothermal Ablation. ACS Applied Bio Materials. 2019, 2, 747-756.

11. R Li, Y Feng*, G Pan*, L Liu*. Advances in Molecularly Imprinting Technology for Bioanalytical Applications. Sensors. 2019, 19, 177 (1-34).

12. J Wang, Z Zhang, H Zhang, C Li, M Chen, L Liu*, M Dong*. Enhanced Photoresponsive Graphene Oxide-Modified g-C3N4 for Disassembly of Amyloid β Fibrils. ACS Appl. Mater. Interfaces. 2018, 11, 96-103.

13. Y Feng, H Wang, J Zhang, Y Song, M Meng, J Mi, H Yin, L Liu*. Bioinspired synthesis of Au nanostructures templated from amyloid β peptide assembly with enhanced catalytic activity. Biomacromolecules. 2018, 19, 2432-2442.

14. T Wang, L Zhang, J Wang, Y Feng, E Xu, X Mao*, L Liu*. Evaluation of the photo-degradation of Alzheimer's amyloid fibrils with a label-free approach. Chemical Communications. 2018, 54, 13084-13087

15. Jie Zhang, Yonghai Feng*, Jianli Mi, Y Shen, Zhigang Tu, Lei Liu*. Photothermal lysis of pathogenic bacteria by platinum nanodots decorated gold nanorods under near infrared irradiation. Journal of Hazardous Materials. 2018, 342, 121-130. (通讯作者)

16. Q Chen, L Zhang, Y Feng*, F Shi, Y Wang*, P Wang, L Liu*. Dual-functional peptide conjugated gold nanorods for the detection and photothermal ablation of pathogenic bacteria. Journal of Materials Chemistry B. 2018, 6, 7643-7651.

17. J Wang, Lei Liu*, D Ge H Zhang, Y Zhang, Y Feng, M Chen, M Dong*, Differential Modulating Effect of MoS2 on the Assemblies of Amyloid Peptides. Chemistry-A European Journal. 2018, 24, 3397-3402

18. Yongxiu Song, Ping Li, Lei Liu*, Christian Bortolini, Mingdong Dong*. Nanostructural Differentiation and Toxicity of Amyloid-β25-35 Aggregates Ensue from Distinct Secondary Conformation. Scientific Reports. 2018, 8:765, DOI: 10.1038/s41598-017-19106-y

19. HX Zhang, Lei Liu*, J Wang, C Bortolini, M Dong Thermal Effect on the Degradation of hIAPP20-29 Fibrils. Journal of Colloid and Interface Science，2018, 513, 126-132.

20. Y Feng, Lei Liu*, J Zhang, H Aslan, M Dong*.  Photoactive antimicrobial nanomaterials Journal of Materials Chemistry B, 2017, 5, 8631-8652

21. Guodong Yang, Lei Liu*, Jie Wang, Christian Bortolini, Mingdong Dong*. Light-driven porphyrin modulating fibrillation of hIAPP20-19 peptide. Journal of Colloid and Interface Science. 2017, 495, 37-43.

22. J Wang, Z Zhu, C Bortolini, S V Hoffmann, A Amari, H X Zhang, Lei Liu*, Mingdong Dong*. Dimensionality of carbon nanomaterial impacting on the modulation of amyloid peptide assembly. Nanotechnology. 2016, 27, 304001(1-7).

23. Lei Liu^#, Yibao Li^#, Dan Xia, Christian Bortolini, Shuai Zhang, Yanlian Yang, Jan. S.Pedersen, Chen Wang, Flemming Besenbacher, Mingdong Dong*. Self-assembled nanopatch with peptide-organic multilayers and mechanical property. Nanoscale. 2015, 7, 2250-2254.

24. Ruirui Xing, Tifeng Jiao,* Linyin Yan, Guanghui Ma, Lei Liu,* Luru Dai, Junbai Li, Helmuth Möhwald, and Xuehai Yan* Colloidal Gold−Collagen Protein Core−Shell Nanoconjugate: One-Step Biomimetic Synthesis, Layer-by-Layer Assembled Film, and Controlled Cell Growth. ACS Appl. Mater. Interfaces 2015, 7, 24733−24740

25. Lin Lin, Haiying Cui, Hui Zhou, Xuejing Zhang, Christian Bortolini, Menglin Chen, Lei Liu* and Mingdong Dong*. Nanoliposomes containing Eucalyptus citriodora as antibiotic with specific antimicrobial activity. Chem. Commun. 2015, 51, 2653-2655.

26. Wang, J.; Cao, Y. P.; Li, Q.; Liu, L.*; Dong, M. D.*, Size Effect of Graphene Oxide on Modulating Amyloid Peptide Assembly. Chemistry-A European Journal, 2015, 21, 9632-9637.

27. Lin Niu#, Lei Liu# (equal contribution), Meng Xu, Jacob Cramer,Kurt V. Gotherlf, Mingdong Dong, Flemming Besenbacher, Qingdao Zeng, Yanlian Yang, Chen Wang*. Transformation of beta sheet structure of amyloid peptide induced by molecular modulators. Chem. Commun. 2014, 50, 8923-8926.

28. Qiang Li^#, Lei Liu^#(equal contribution), Shuai Zhang, Meng Xu, Xueqing Wang, Chen Wang, Flemming Besenbacher, Mingdong Dong*. Modulating Aβ33-42 peptide assembly by graphene oxide. Chemistry-A European Journal, 2014, 20, 7236-7240.

29. Guanghong Zeng^#, Lei Liu^# (equal contribution), Dan Xia, Qiang Li, Zhuo Xin, JianGuo Wang, Flemming Besenbacher, Troels Skrydstrup and Mingdong Dong*. Transition of Chemically modified diphenylalanine peptide assemblies revealed by atomic force microscopy. RSC Adv. 2014, 4, 7516-7520.

30. Lei Liu, Dan Xia, Lasse H. Klausen, Mingdong Dong* The Self-Assembled Behavior of DNA Bases on the Interface. Int. J. Mol. Sci. 2014, 15, 1901-1914.

31. Lin Lin, Haiying Cui, Hui Zhou, Xuejing Zhang, Christian Bortolini, Menglin Chen, Lei Liu* and Mingdong Dong*. Nanoliposomes containing Eucalyptus citriodora as antibiotic with specific antimicrobial activity. Chem. Commun. 2015, 51, 2653-2655. (corresponding author)

32. Lin Niu^#, Lei Liu^# (equal contribution), Meng Xu, Jacob Cramer,Kurt V. Gotherlf, Mingdong Dong, Flemming Besenbacher, Qingdao Zeng, Yanlian Yang, Chen Wang*. Transformation of beta sheet structure of amyloid peptide induced by molecular modulators. Chem. Commun. 2014, 50, 8923-8926.

33. YinLi Li^#，Lei Liu^#,(equal contribution), Ramesh Subramani, Yunxiang Pan, Bo Liu, Yanlian Yang, Chen Wang, Wael Mamdouh, Flemming Besenbacher and Mingdong Dong*. Building layer-by-layer 3D supramolecular nanostructures at the terephthalic acid/stearic acid interface. Chem. Commun. 2011, 47, 9155-9157.